Topic Drug

Teacher lesson

Patient Concept Example dose 1x pulse 70 kg

Score 0 In range 0% Clock 0 h Half-life 2 h

Round ready Tap dose to enter the window

Dose size 1x

0.25x 1x 1.5x

Frequency q6h Risk Low effect Goal Relative

Guided demo

Watch how PKWise turns dosing choices into a response curve.

Choose how to play

Keep the drug curve in range

Try a 36-hour case, or choose Endure for a longer challenge.

Demo drug starts a guided walkthrough of the controls, dosing choices, and recorded curve.

Educational use only — simplified pharmacology, not clinical guidance. Drug information and pharmacokinetics are simplified and heuristically approximated.

Teacher setup

Choose a starting lesson for your cohort. A lesson link opens these settings; individual play remains available through Leave lesson.

Level Topic Medicine Run

Scheduled change

Include this change Change at hour (2–30)Leave blank to use the example’s usual time. Pause at the change to review the curve

Student link

Scheduled change

The curve shows the simplified model’s recorded response. Watch its slope and target band before and after the flag; use Slow for more time to compare.

How to Play

Dose, watch, adjust

Choose a topic and medicine, then press Dose to start. Each dose repeats at the selected interval. Adjust size and timing to keep the response in the green target band.

Curve: the whole recorded profile stays visible in a 36-hour case. Endure shows the most recent 32 hours. The dot marks now, not a prediction.
Levels: Concept uses relative pulses. Clinical adds example doses and body mass. Expert adds plasma and effect curves, absorption, and extra dosing controls.
Orange flag: a scheduled change. Open the event details above the graph to see what will happen. Case settings let you change its time or turn it off before restarting.
Absorption depot: the yellow dashed line in Expert is the relative amount awaiting absorption, not a blood concentration.
Pause: stops the clock. In Expert, Skip next withholds one automatic dose while time continues.
Loading dose (2×): a larger first pulse for this teaching model, available once at the start. Dose uses your selected size for subsequent doses. The 2× example is not a clinical loading-dose formula.

Educational use only — simplified pharmacology, not clinical guidance. Drug information and pharmacokinetics are simplified and heuristically approximated.

About PKWise

PKWise was created by PharmaNUS as an intuitive pharmacokinetics learning game for medical and health professions learners.

Educational purpose PKWise helps learners build intuition for half-life, therapeutic windows, interactions, and dose timing.

Learning design Fast visual feedback connects dosing decisions with simplified concentration-time curves.

Install PKWise

Add PKWise to your home screen or desktop for quick access.

Open PKWise to install

Local browser data: Clearing local browser data, site data, cache, or storage for this app may erase stats, streaks, and progress history on this device.

Disclaimer: Educational use only. Content is simplified for learning and gameplay and may not reflect the full complexity of medicines, patients, local formularies, institutional policies, product information, or current guidance. This app does not provide medical advice, clinical decision support, prescribing guidance, dispensing authority, dosing, contraindication, interaction, or monitoring recommendations. For real patient care, consult current official references and a qualified healthcare professional.

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Core idea

Dose, then watch exponential fall

Keep the curve in the green therapeutic band. Short half-life drugs fall fast and usually need closer timing.

Run complete

PK rhythm captured

You kept the curve in range.

Panel note loading.

Score 0 In range 0% Best streak 0 h

Runs 0 | Best 0%

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